| 名稱 | Recombinant Human FGF-acidic |
| 型號(hào) | |
| 更新時(shí)間 | 2023-09-24 |
| 特點(diǎn) | FGF-acidic是23已知FGF家族的成員之一。這個(gè)家庭中發(fā)揮核心作用的蛋白質(zhì)在產(chǎn)前發(fā)展和產(chǎn)后的生長(zhǎng)和再生各種組織,通過(guò)促進(jìn)細(xì)胞增殖和分化。FGF-acidic non-glycosylated肝素結(jié)合生長(zhǎng)因子,表示在大腦中,腎、視網(wǎng)膜、平滑肌細(xì)胞,骨基質(zhì),成骨細(xì)胞、星形膠質(zhì)細(xì)胞和內(nèi)皮細(xì)胞。FGF-acidic有能力通過(guò)所有的FGF受體信號(hào)。} |
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一.產(chǎn)品名稱：Recombinant Human FGF-acidic
二.貨號(hào)Catalog Number:AF-100-17A
三.產(chǎn)地：美國(guó)Peprotech
四.同義Synonyms:Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta
五.描述Description:
FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant human FGF-acidic is a 16.0 kDa protein consisting of 141 amino acid residues. Manufactured using all non-animal reagents.
六.AA序列AA Sequence:
MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
七.來(lái)源Source:E.coli
八.純度Purity:Greater than 95% by SDS-PAGE gel and HPLC analyses.
九.生物活性Biological Activity:
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 10ng/ml corresponding to a specific activity of ≥ 1 x 105 units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.5 ng/ml in the presence of 10 μg/ml heparin, corresponding to a specific activity of ≥ 2 x 106 units/mg.
十.交叉性Cross Reactivity:
Cow, Mouse, Pig, Rat, Shark, Squid, Human
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聯(lián)系人：李小姐
電話/傳真：13366128764
手機(jī)：15311648455
地址：北京市海淀區(qū)廂黃旗2號(hào)樓1層4-179室
電話/傳真：13366128764
手機(jī)：15311648455
地址：北京市海淀區(qū)廂黃旗2號(hào)樓1層4-179室